Anti Cancer intermediates

Anti Cancer intermediates
NO.	Intermediate Name	CAS NO	API/END USE
1	6-bromonicotinaldehyde	149806-06-4	Abemaciclib
2	5-((4-ethylpiperazine-1yl) methyl)pyridin-2amine	1180132-17-5
3	6-bromo-4-fluoro-1-isopropyl-2-methyl-1h-benzo[d]imidazole	1231930-33-8
4	4-fluoro-1-isopropyl-2-methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-benzo[d]imidazole	1231930-37-2
5	Ethyl 4-(1-methyl-5-nitro-1H-benzo[d] imidazol-2-yl)butanoate	3543-72-4	Bendamustine
6	Ethyl4-(5-amino-1-methyl-1H-benzo[d]imidazole -2-yl)butanoate	3543-73-5
7	Isopropyl 4-(5-amino-1-methyl-1H-benzo[d]imidazol-2-yl)butanoate	1313020-26-6
8	4-chloro-6,7-dimethoxyquinoline	35654-56-9	Cabozantinib
9	4-Hydroxy-6,7-dimethoxyqunioline	13425-93-9	Cabozantinib
10	2-(N-BOC)-Aminothiazole-5-carboxylic acid	302964-02-9	Dasatinib
11	(E)-N-(2-Chloro-6-Methyl Phenyl)-3-Ethoxy Acrylamide	863127-76-8
12	2-Amino-N-(2-chloro-6-methylphenyl)thiazole-5-carboxamide	302964-24-5
13	4,6-dichloro-2-methylpyrimidine	1780-26-3
14	4-Aminopyrazolo[3,4-d]pyrimidine	2380-63-4	Ibrutinib
15	3-(4-Phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine	330786-24-8
16	tert-butyl (S)-3-hydroxypiperidine-1-carboxylate	143900-44-1
17	4-Amino-3-iodopyrazolo[3,4-d]pyrimidine	151266-23-8
18	4-Phenoxyphenylboronic acid	51067-38-0
19	4-Phenoxybenzoic acid	2215-77-2
20	(ethane-1,2-diylbis(oxy)) bis(ethane-2,1-diyl) bis(4-methylbenzenesulfonate)	19249-03-7	Icotinib
21	4-[(4-Methylpiperazin-1-yl)-methyl]-benzoic acid dihydrochloride	106261-49-8	Imatinib
22	N-(5-Amino-2-methylphenyl)-4-(3-pyridyl)-2-pyrimidineamine	152460-10-1	Imatinib
23	Etyl-3-guanidino-4-methyl-benzoate nitrate	641569-96-2	Nilotinib
24	3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl) aniline	641571-11-1
25	3-dimethylamino-1-(3-pyridyl)-2-propen-1-one	55314-16-4
26	4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)benzoic acid	641569-94-0
27	L-Glutamic acid diethyl ester hydrochloride	1118-89-4	Pemetrexed
28	2-[(4-Bromophenyl)methoxymethylene]propanedinitrile	1188083-45-5	Pirtobrutinib
29	2-Chloro-7-cyclopentyl-N,N-dimethyl-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide	1211443-61-6	Ribociclib
30	Phenyl phenylcarbamate	4930-34-4	Ripretinib
31	N-(3-chloro-4-fluorophenyl)-7-fluoro-6-nitroquinazolin-4-amine	162012-67-1	Afatinib
32	2-Fluoro-5-formylbenzonitrile	218301-22-5	Olaparib
33	(3-Oxo-1,3-dihydro-isobenzofuran-1-yl)-phosphonic acid dimethyl ester	61260-15-9	Olaparib
34	Methyl 2-oxoindole-6-carboxylate	14192-26-8	Nintedanib
35	N-(4-Aminophenyl)-N-methyl-2-(4-methylpiperazin-1-yl)acetamide	262368-30-9	Nintedanib
36	tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate	571188-59-5	Palbociclib
37	6-Bromo-2-chloro-8-cyclopentyl-5-methylpyrido[2,3-d]pyrimidin-7(8H)-one	1016636-76-2	Palbociclib
38	4-Amino-3-chlorophenol	17609-80-2	Lenvatinib
39	4-Amino-3-chlorophenol hydrochloride	52671-64-4
40	4-Chloro-7-methoxyquinoline-6-carboxamide	417721-36-9
41	N-(3-Chloropropyl)morpholine	7357-67-7	Gefitinib
42	4-Methoxy-5-(3-morpholinopropoxy)-2-nitrobenzonitrile	675126-26-8
43	3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate	179688-53-0
44	2,4-Dichloro-5-methoxyaniline	98446-49-2	Bosutinib
45	4-Chloro-7-(3-chloropropoxy)-6-methoxyquinoline-3-carbonitrile	214470-68-5	Bosutinib
46	3-Aminophenylacetylene	54060-30-9	Erlotinib
47	6,7-Bis(2-methoxyethoxy)quinazolin-4(3H)-one	179688-29-0
48	Ethyl 2-amino-4,5-bis(2-methoxyethoxy)benzoate hydrochloride	183322-17-0
49	[5-Bromo-3-[(1R)-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-yl]amine	877399-00-3	Crizotinib
50	tert-Butyl 4-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl]piperidine-1-carboxyla	877399-74-1	Crizotinib
51	(E)-6-Nitro-3-[2-(pyridin-2-yl)ethenyl]-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole	886230-75-7	Axitinib
52	6-Iodo-1H-indazole	261953-36-0	Axitinib
53	5-[4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-furaldehyde	231278-84-5	Lapatinib
54	(5-Formylfuran-2-yl)boronic acid	27329-70-0
55	N-[3-Chloro-4-(3-fluorobenzyloxy)phenyl]-6-iodoquinazolin-4-amine	231278-20-9
56	6-Iodoquinazolin-4-one	16064-08-7
57	3-Chloro-4-(3-fluorobenzyloxy)aniline	202197-26-0
58	3-(2-Chloropyrimidin-4-yl)-1-methylindole	1032452-86-0	Osimertinib
59	4-Fluoro-2-methoxy-5-nitroaniline	1075705-01-9	Osimertinib
60	3-Amino-6-methylbenzenesulfonamide	6973-09-7	Pazopanib
61	N-(2-Chloropyrimidin-4-yl)-N,2,3-trimethyl-2H-indazol-6-amine	444731-75-3
62	2,3-Dimethyl-2H-indazol-6-amine hydrochloride	635702-60-2
63	5-Fluoroindolin-2-one	56341-41-4	Sunitinib
64	5-Formyl-2,4-dimethyl-1H-pyrrole-3-carboxylic acid	253870-02-9	Sunitinib
65	4-(4-Bromo-2-fluoroanilino)-7-hydroxy-6-methoxyquinazoline	196603-96-0	Vandetanib

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